The American road race is scheduled to start on May 16, with the Giro - the world's second-biggest stage race - getting underway on May 8 in Amsterdam. "I've decided to ride the Tour of California in 2010," the 38-year-old told Twitter.
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Armstrong's decision to compete in California suggests he is not planning to reprise the schedule he undertook this season when he rode the Giro for the first time as part of his comeback after three-and-a-half-years in retirement. He came home 12th in the event before going on to finish third in the Tour de France behind Alberto Contador and Andy Schleck. Armstrong - a seven-time winner of the Tour de France raced for Astana this year, but has set up the new RadioShack team for whom he will compete next season.